boot - How to install Ubuntu 18.04 on a new system with blank hard drive, will I have UEFI issues?

I want to buy a new computer with an ASUS motherboard, and install on it Ubuntu 18.04. The hard drive will be blank with no operating system installed and not even formatted. Will I have any issues with secure boot? The firmware supports UEFI and I guess that the secure boot feature will initially be enabled.